The 2022 Nobel Prize in Chemistry has been awarded to David Baker of the University of Washington and Demis Hassabis of DeepMind for their pioneering work in developing artificial intelligence (AI) methods for predicting the 3D structures of biological molecules. Baker developed computer models that can accurately predict the complex twists and folds of proteins, a problem that has long challenged scientists. Hassabis, the co-founder of DeepMind, developed AI systems that can determine a protein’s 3D structure from its amino acid sequence, a breakthrough that could accelerate the development of new drugs. Their work has enabled researchers to understand how diseases emerge and advance the field of drug discovery. The Nobel committee praised their contributions, stating that they “have taken computational models for structure determination to a new level.” This year’s chemistry prize highlights the growing importance of AI and machine learning in scientific research.