The European Union’s top court on Wednesday rejected Google’s appeal of a record $4.3 billion antitrust fine from regulators who found the company unfairly promoted its own mobile apps on Android smartphones. The European Court of Justice’s ruling is a major legal victory for the EU’s antitrust chief, Margrethe Vestager, in her campaign for tougher regulation of big technology companies. The court upheld the European Commission’s 2018 ruling that Google imposed “unlawful restrictions on manufacturers of Android mobile devices” to benefit its own services, particularly on mobile apps for browsing the web and playing videos. Google was accused of requiring smartphone makers to pre-install its apps and services on Android devices and preventing them from selling phones with altered versions of Android. The court agreed there are “very specific constraints” that Google imposed as a condition for licensing its app store. Google was fined a record 4.34 billion euros ($4.3 billion) by the European Commission in 2018 in the case, one of three antitrust penalties totaling more than $8 billion that it has received from the EU’s executive branch.